Synthesis of (+)-Crocacin C

doi:10.1055/s-0029-1220105

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Synfacts 2010(7): 0744-0744
DOI: 10.1055/s-0029-1220105

Synthesis of Natural Products and Potential Drugs

Synthesis of (+)-Crocacin C

Contributor(s): Steven V. Ley, Catherine F. Carter
M. Candy, G. Audran, H. Bienaymé, C. Bressy*, J.-M. Pons*
Aix-Marseille Université, France

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Publication History

Publication Date:
22 June 2010 (online)

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Significance

(+)-Crocacin C was isolated from Chondromyces crocatus and Chondromyces pediulatus in 1994 and displays moderate antifungal, antibacterial, and cytotoxic activities. The total synthesis is achieved here in an impressive 22.3% overall yield.